Inhibitors for Novel Coronavirus ProteaseIdentified by Virtual Screening of 687 MillionCompounds
March 6, 2020 at 4:25 pm
The Basel University research (published 03.03.2020) declares TAXIFOLIN as one of 11 compounds showing the most efficient inhibition of SARS viruses activity.
Extract from Original:
"The sibirian larch (Larix sibirica) is known to produce (-)-taxofolin offering a natural resource for its extraction. Furthermore, food preparations containing (-)-taxifolin are readily available from pharmacies and other companies allowing direct and fast access to the potential antiviral. Remarkably, (-)-taxofolin underwent seven hydrogen bonds which represent the highest count in our selection of compounds. Since hydrogen bonds are a key determinant for drug specificity,29 (-)-taxifolin might offer a naturally occurring alternative to the proposed inhibitors CP-1 to CP-11."