Дигидрокверцетин (ДГК) - получают из сибирской лиственницы запатентованным инновационным методом разработанным ведущими учеными биологами МГУ им. Ломоносова.
Метод исключает нарушение природных - нативных свойств ДГК. Высочайшая чистота препарата не менее 98,0%, с максимальной антиоксидантной активностью - 32 000 - 64 000 µM TE/g ORAC и отсутствием побочных эффектов.
Применение Дигидрокверцетина чистотой 98%
Дигидрокверцетин не лекарство.
Product name |
Marketing name |
Production date |
Distributor |
Country of origin |
|
DIHYDROQUERCETIN Customs code 2932.99.0090 FDA code: 54YCZ07 CAS 480-18-2 |
Taxifolin (Dihydroquercetin) |
May, 2017 |
|
Balinvest Ltd. |
RUSSIA |
GENERAL
INFORMATION |
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Name |
DIHYDROQUERCETIN Synonyms: (+)-Dihydroquercetin;
(+)-Taxifolin; Taxifolin; trans-Dihydroquercetin; IUPAC Name: (2R,3R
)-2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-2,3-dihydro-4H-chromen-4-one Systematic Name: (2R,3R)-2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-2,3-dihydro-4H-1-benzopyran-4-one. |
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INCI name |
Dihydroquercitin |
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Molecular
Formula |
C15H12O7 |
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Molecular
Weight, g/mol |
304.0583 |
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CAS Number |
480-18-2
System Generated
Number: 000480182 |
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EINECS Number |
207-543-4 |
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FDA Number |
54YCZ07 |
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RTECS |
LK6920000 |
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Botanical
Source |
Not genetically modified plant: Larch
species: L. dahurica L., L.
gmelinii, L. sibirica ledeb. Used part: sawlogs. Preparation: Spray dried
extract |
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Extraction process |
The
patented extraction process chain uses food grade ethanol and water as
solvents in a multistep process. The purified aqueous extract is spray dried
and represents fine, yellowish-colored powder with an aromatic smell and mild
bitter taste. |
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Sterilization |
DIHYDROQUERCETIN
is not subject of sterilization and radiation |
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Contact with GMO material |
None:
Manufacturer does not process any GMO modified material |
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Long Term Storage: |
At +4 0C
up to 20 0C
|
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Stability |
This
product is stable for 5 years as manufactured |
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Handling |
Protect
from light, store in a dry, cool place |
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DESCRIPTORS |
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Density |
1.182142759 |
Potential
energy (kcal/mol) |
73.8359227 |
|
Number of
rings |
3 |
Number of
atoms |
34 |
|
Chiral
atoms |
2 |
Acidic atoms |
0 |
|
H-bond
donor |
5 |
H-bond acceptor |
7 |
|
Basic atoms |
0 |
Aromatic atoms |
12 |
|
Heavy atoms |
22 |
Number of
bonds |
36 |
|
Single
bonds |
23 |
Rotatable single bonds |
1 |
|
Double
bonds |
0 |
Triple
bonds |
0 |
|
Aromatic
bonds |
12 |
Topological Polar Surface Area |
128 |
|
λmax |
A solution
in ethanol R shows an absorption maximum (2.2.25) at 290 nm and
at 340 nm |
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Product Specific References |
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Botanical
functions |
DIHYDROQUERCETIN
is a key dihydroflavonol intermediate between FLAVONOLS and FLAVANOLIGNINS.
An NADPH-dependent dihydroflavonol 4-reductase catalyses the formation of
leucocyanidin (Flavan 3,4-diol) structure. |
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Product
Description |
Antioxidant
bioflavonoid. Metal chelator. ORAChydro
is over 32.000 μM TE/g |
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Major uses: |
Dihydroquercetin,
a yellowish crystalline pentahydroxy-flavanone, occurring in large quantities
in Larix species, Douglas fir and Jeffrey pine barks, was found to be an
effective antioxidant for lard, cottonseed oil, and butter oil. This compound
imparts no taste and color to fats and oils and appears to be nontoxic. Dihydroquercetin is the
non-nutrient antioxidant, relating to flavonoids, which occur in food and
which may be significant in the overall antioxidative protection afforded by
the diet. This benefit may be conferred in three main ways: (1) As antioxidant in
food during storage and in the gastrointestinal tract; (2) As antioxidants in
the human body; (3) By providing
protection in food against oxidation as well as acting as true antioxidant. |
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Environment |
Larch forests growing in |
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Product
Specific Literature References |
Interaction
of flavonoids with ascorbate and determination of their univalent redox
potentials: a pulse radiolysis study: Suppression
of active oxygen-induced cytotoxicity by flavonoids: T. Nakayama, et al.; Biochem. Pharmacol. 45,
265 (1993) Structure-antioxidant
activity relationships of flavonoids and phenolic acids: C.A. Rice-Evans, et al.; Free Radical Biol. &
Med. 20, 933 (1996), (Review) |