Larch Arabinogalactan is a highly branched polysaccharide or fiber derived from the Larch Tree (Larix species), with low molecular weight, consisting of a galactan backbone with side-chains of galactose & arabinose sugar.
It supports proper immune system function by:
Chemical formula: C20H36O14; molecular weight: 500,491
With an authenticity of the chemical structure‚ Larch Arabinogalactan is resistant to herbicides, pesticides‚ heavy metals‚ most bacteria‚ yeast and mold counts‚ but readily soluble in the metabolic processes in humans and animals.
The longest recognized use of Larch Arabinogalactan is a source of dietary fiber. It has been shown to increase the production of short-chain fatty acids (SCFA's), principally butyrate and propionate, minimize ammonia production and absorption. These special fatty acids are critically important for the health of the colon. In fact, having an adequate supply of SCFA's is thought to make colon cells more resistant to both tumor promotion and a variety of intestinal disease.
Larch Arabinogalactan also acts as a food supply for friendly bacteria. The term used to describe this action is "probiotic." The most well-known probiotic substance is "fructo-oligosaccharides" or "FOS." Larch Arabinogalactan acts in the same manner as FOS in humans, offering significant positive effect on gut micro-floral balance. Specifically, this fiber acts to increase good bacteria like bifid-bacteria and lactobacillus, while decreasing bad bacteria. Since these friendly bacteria are critically important for the health of digestive and immune systems, detoxification and hormone regulating capabilities, nutrient formation and absorption, the growth promoting effects of Larch Arabinogalactan on these organisms alone makes it a valuable addition to the human and animals diet.
A healthy immune system is, in many respects, the core of prevention or resistance against disease, and immune system health is all about "balance."
Substances, which promote a balanced response to stress, are called "adapto-gens." Larch Arabinogalactan appears to act as an "adapto-genic" agent on the immune system, lifting up weak aspects, making the balance of the immune system, with an ability to build a more responsive immune system, against viruses, bacteria, and parasites, and support the body’s defense against free radicals that are produced in the body due to stress, pollutants, toxins, and from normal cellular processes.
Larch Arabinogalactan has significatelly effect against infections, including the common cold, flu, H1N1(swine) flu, ear infections in children, and HIV/AIDS, liver cancer, brain condition caused by liver damage (hepatic encephalopathy), dietary fiber, lower cholesterol, and to boost the immune system.
Larch Arabinogalactan is used as a stabilizer, binder, and sweetener, prevent oxidation processes, scientifically increase the nutritional and health values of food and drinks, and through digestion, increase and boost the immune system.
Larch Arabinogalactan is not derived from GMO products or produced using GMO ‘s or their derivatives, free from BSE (Bovine spongiform encephalopathy - known as mad cow disease), gluten free, hydrogenated oils free, preservative free.
Arabinogalactan in the pharmaceutical industry used in two ways:
1) As an auxiliary component
Having membranotropic properties and could prospectively be used as
"carriers" of drugs. Arabinogalactan allows to increase the solubility
sparingly soluble medicinal substances.
Arabinogalactan is a dietary Supplement that has a wide range of biological activity: gastroprotective, immunobiological properties. That is why the use of arabinogalactan as a carrier allows you to significantly expand the range of composite dosage forms and to improve their performance.
Arabinogalactan is also used as a binding nontoxic agent for tabletting dosage forms with high strength. Arabinogalactan enhances the activity and effectiveness the release of various water-soluble drugs. It is used to improve absorbability other drugs with low bioavailability. In addition, having mefloquineuine and dispersing properties, arabinogalactan is used as an emulsifier stabilization of emulsions.
2) As a separate component
Arabinogalactan can be used as the main component of biologically active additives used for prevention of cardiovascular, respiratory, infectious disease; the normalization of the gastrointestinal tract; enhancing the immune system.
Studies have shown that arabinogalactan derived from Siberian larch, stimulates the activity of natural killer cells, cytokines and macrophages.
Natural killers – NK-lymphocytes, large lymphocytes with cytotoxicity against tumor cells and cells infected with viruses are one of the most important components of cellular innate immunity.
Cytokines regulate intercellular and intersystem interactions determine cell survival, stimulation or the suppression of their growth, differentiation, functional activity and apoptosis, as well as provide consistency the action of the immune, endocrine and nervous systems in normal conditions and in response to pathological effects.
Macrophages – cells capable of active capture and digestion of bacteria, debris dead cells and other foreign or toxic to the body particles.
Arabinogalactan supports the natural immune function, helps to increase the number of active immune cells and the production of antibodies based on the T-regulatory cells, T-suppressor cells to call appropriate immune response.
It stimulates the activity of natural killer cells (cytotoxic lymphocytes).
Arabinogalactan allows to induce circulation of a number of cytokines such as interferon gamma (Ifny), necrosis factor the tumor (TNF) and various interleukins (IL1, or IL6).
It also supports the functioning of macrophages, which are important elements in protective systems body.
It also increases the level of leukocytes. Studies have shown that arabinogalactan significantly increases the number circulating white blood cells. This is primarily related to an increase in the concentration of neutrophils.
Recent studies have shown that arabinogalactan causes the adaptive immune response to specific antigens.
In particular, a higher immune response immunoglobulin G vaccine was observed during 10 weeks after vaccination.